两者区别：be careful with表示做某事时很小心、仔细或对某人某物很关心。with后接名词或动名词，be careful of意思是当心；留意；注意，后接名词、动名词或从句，形容人很细心。

be careful with造句：

You are careful with my cat。你对我的猫很关心。

Weve got to be careful with everything we do。我们做任何事都要仔细。

Be careful with that knife.Its got a keen edge。小心那把刀子，他有锐利的锋刃。

be careful of造句：

Be careful of the dog，it sometimes bites people。当心那条狗，它有时候会咬人。

Be careful of that sinister man，He is dangerous。留意那个阴险的人，他很危险。

You must be careful of your health。你一定要注意你的健康。

标签：be careful withbe careful ofbe careful with和be careful of的区别